Associate Medical Director/Medical Director, Early phase, Clinical Science

Description

ACCOUNTABILITIES

 Lead or provide core clinical science support for Phase 1a/b and Phase 2a studies in Asia/China, including healthy volunteer. early patient trials, proof-of-concept studies, biomarker-driven studies,.
 Contribute to early phase clinical development plans, protocol synopses, and protocols, with specific input on patient population, endpoint selection, dose strategy, PK/PD sampling, biomarker
integration, and stopping rules.

 Provide medical and scientific oversight during study conduct, including review of eligibility questions, protocol deviations, emerging safety signals, and dose-escalation, dose-optimization, or
cohort-expansion decisions in collaboration with the study team.
 Interpret and communicate early clinical data, including safety, tolerability, PK, PD, biomarker, and preliminary efficacy results, to assess mechanism, establish early proof-of-concept, and support
timely development dec...