Bioinformatics Engineer (Hybrid)

Bioinformatics Engineer – T2T Genome Assembly (Non-Model Organisms) Location: Foster City CA/Hybrid (as applicable) Duration: 12-Month Contract We are seeking a highly skilled Bioinformatics Engineer to support the development of Telomere-to-Telomere (T2T) reference genomes for non-model organisms. This role will focus on building, optimizing, and operating long-read genome assembly and curation pipelines using PacBio HiFi and/or Oxford Nanopore sequencing data, while collaborating closely with wet-lab and computational biology teams. Key Responsibilities Design and execute genome assembly strategies for non-model organisms, including data quality assessment, genome profiling, contamination screening, and sequencing recommendations. Perform long-read genome assemblies using tools such as Hifiasm, Verkko, Flye, and Canu, driving assemblies toward chromosome-scale and T2T-quality results. Resolve haplotypes and complex genome structures, including highly heterozygous and polyploid gen...