Position located in Boston, MA
Contract Opportunity
Responsibilities of the Contract Principal AI/ML Scientist (Antibody Engineering):
Design and implement the computational platform architecture for antibody discovery, integrating ML/DL models, structural biology tools, and high-throughput screening data analysis into the pipelineDevelop and deploy ML models for antibody-antigen binding prediction, affinity maturation, and developability assessmentDevelop state-of-the-art deep learning models for structure-based antibody design, antibody sequence design, antibody-antigen co-folding, and antibody-antigen binding predictionLead the integration of AlphaFold, Rosetta Antibody/Rosetta Fold, Boltz-1, and other state-of-the-art protein structure prediction tools into the discovery pipelineCreate and maintain computational workflows for analyzing large-scale screening data (phage display, yeast display, ...