Research Fellow (Postdoctoral Researcher)

Trinity is Ireland’s leading university and is ranked 75th in the world (QS World University Rankings 2026). Founded in 1592, the University is steeped in history with a reputation for excellence in education, research, and innovation, which has been inspiring generations of thinkers for over 400 years. The Ryan Lab investigates how pathogenic mitochondrial DNA mutations influence innate immune function, inflammatory responses, cellular metabolism, and susceptibility to infection. The lab uses primary macrophage models, mouse models of mitochondrial disease, immunological assays, metabolic phenotyping, molecular biology, and multi-omics approaches to understand how inherited mitochondrial defects reshape innate immune signalling and inflammatory disease susceptibility. This postdoctoral role will focus on defining how pathogenic mitochondrial DNA mutations alter macrophage function, innate immune signalling, type I interferon responses, inflammatory cytokine production, cellular metabo...